Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 2/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25228119 | 1.00 | BRD4 (0.45) | BRD4MAPK14METALDH1A1PDE4B | |
| SCHEMBL29537119 | 0.85 | MAPK14 (0.57) | MAPK14MET | |
| SCHEMBL13239748 | 0.85 | MAPK14 (0.57) | MAPK14MET | |
| SCHEMBL29537098 | 0.77 | MET (0.40) | BRD4METALDH1A1PDE4BAXL | |
| SCHEMBL25227027 | 0.77 | MET (0.40) | BRD4METALDH1A1PDE4BAXL | |
| SCHEMBL30640268 | 0.75 | MAPK14 (0.41) | MAPK14METALDH1A1PDE4B | |
| SCHEMBL6073545 | 0.72 | HPGD (0.40) | MAPK14ALDH1A1PDE4B | |
| SCHEMBL29536806 | 0.69 | PDE4B (0.40) | BRD4METALDH1A1PDE4BPLA2G7 | |
| SCHEMBL25420084 | 0.69 | PDE4B (0.40) | BRD4METALDH1A1PDE4BPLA2G7 | |
| SCHEMBL5458537 | 0.69 | NPC1 (0.45) | ALDH1A1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032071-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORPORATION (US) | 2022-02-10 | — | — | WO | disclosed |