Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365948 | 0.83 | NPC1 (0.48) | NPC1RAB9AGAALMNAMAPT | |
| SCHEMBL30545052 | 0.82 | L3MBTL1 (0.46) | L3MBTL1POLBMAPK1NPC1RAB9A | |
| SCHEMBL29114314 | 0.82 | NPC1 (0.45) | NPC1RAB9A | |
| SCHEMBL31348009 | 0.79 | NPC1 (0.67) | L3MBTL1POLBMAPK1NPC1RAB9A | |
| SCHEMBL30545040 | 0.74 | ADORA2A (0.61) | L3MBTL1POLBMAPK1NPC1RAB9A | |
| SCHEMBL29544272 | 0.73 | BAZ2B (0.38) | KMT2A | |
| SCHEMBL7936130 | 0.73 | NPC1 (0.46) | POLBNPC1RAB9AGAALMNA | |
| SCHEMBL30545053 | 0.71 | RAB9A (0.47) | L3MBTL1NPC1RAB9ASRD5A2GAA | |
| SCHEMBL6324751 | 0.69 | SRD5A2 (0.51) | L3MBTL1POLBMAPK1SRD5A2GAA | |
| SCHEMBL6220407 | 0.69 | MAPK1 (0.51) | L3MBTL1POLBMAPK1SRD5A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105936-B | Imidazo [1,2-a ] pyridine compound serving as FLT3 inhibitor, and preparation method and application thereof | 遵义医科大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-117105936-A | Imidazo [1,2-a ] pyridine compound serving as FLT3 inhibitor, and preparation method and application thereof | 遵义医科大学 | 2023-11-24 | — | — | CN | disclosed |