Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MARK4 | Q96L34 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20377223 | 0.82 | RAB9A (0.76) | NPC1RAB9AADORA2APOLBPKM | |
| SCHEMBL1355332 | 0.82 | NPC1 (0.76) | NPC1RAB9AADORA2APOLBEPHB3 | |
| SCHEMBL31348008 | 0.81 | NPC1 (0.74) | NPC1RAB9AADORA2APOLBPKM | |
| SCHEMBL31365954 | 0.81 | NPC1 (0.74) | NPC1RAB9AADORA2APOLBEPHB3 | |
| SCHEMBL31365952 | 0.81 | RAB9A (1.00) | NPC1RAB9AADORA2APOLBL3MBTL1 | |
| SCHEMBL31365955 | 0.81 | NPC1 (0.74) | NPC1RAB9AADORA2APOLBPKM | |
| SCHEMBL31365958 | 0.81 | NPC1 (0.74) | NPC1RAB9AADORA2APOLBPKM | |
| SCHEMBL31348010 | 0.81 | NPC1 (0.74) | NPC1RAB9AADORA2APOLBPKM | |
| SCHEMBL30545040 | 0.80 | ADORA2A (0.61) | NPC1RAB9AADORA2APOLBMAPK1 | |
| SCHEMBL30642385 | 0.79 | L3MBTL1 (0.43) | NPC1RAB9APOLBMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655626-B | Cyclopropanamide compound containing imidazo [ l,2-a ] pyridine skeleton and preparation method and application thereof | 遵义医科大学 | 2025-03-11 | — | — | CN | disclosed |
| CN-117105936-B | Imidazo [1,2-a ] pyridine compound serving as FLT3 inhibitor, and preparation method and application thereof | 遵义医科大学 | 2025-01-24 | — | — | CN | disclosed |