Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757072 | 0.87 | — | — | |
| SCHEMBL28462462 | 0.79 | NPSR1 (0.38) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL27568155 | 0.79 | GAA (0.38) | ALDH1A1SMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL28165012 | 0.79 | MGLL (0.35) | TSHRMGLLL3MBTL1 | |
| SCHEMBL30642749 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL27932489 | 0.77 | TRPA1 (0.36) | ALDH1A1HPGD | |
| SCHEMBL2478579 | 0.75 | MEN1 (0.38) | ALDH1A1SMN1; SMN2HPGDTSHRMEN1 | |
| SCHEMBL27860451 | 0.75 | KDM4E (0.39) | SMN1; SMN2TSHRMAPTKMT2AKDM4E | |
| SCHEMBL27314289 | 0.75 | — | — | |
| SCHEMBL27776025 | 0.74 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220640-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-11-16 | — | — | WO | disclosed |