SCHEMBL30643683

SCHEMBL30643683

CC(C)(C)OC(=O)N1CCCC(C2CCN(c3ccc(C4CCC(=O)NC4=O)cc3)CC2)C1

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 10/20 0.55
▸ CRBN Q96SW2 10/20 0.55
▸ GPR119 Q8TDV5 10/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24480733 0.91 GPR119 (0.62) DDB1CRBNGPR119
SCHEMBL26641541 0.86 CRBN (0.45) DDB1CRBN
SCHEMBL21876964 0.85 DDB1 (0.67) DDB1CRBNGPR119
SCHEMBL23301226 0.85 DDB1 (0.67) DDB1CRBNGPR119
SCHEMBL31232850 0.85 CRBN (0.63) DDB1CRBN
SCHEMBL24480896 0.83 DDB1 (0.54) DDB1CRBNGPR119
SCHEMBL30643569 0.83 DDB1 (0.59) DDB1CRBNGPR119
SCHEMBL26641530 0.83 DDB1 (0.59) DDB1CRBNGPR119
SCHEMBL31726711 0.82 DDB1 (0.60) DDB1CRBNGPR119
SCHEMBL29680886 0.82 DDB1 (0.60) DDB1CRBNGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120092003-A CDK protein degrading agents, pharmaceutical compositions and therapeutic uses 拜欧斯瑞克斯公司 2025-06-03 — — CN disclosed
WO-2023220640-A1 CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX, INC. (US) 2023-11-16 — — WO disclosed
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