Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 18/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30644096 | 0.85 | HCRTR2 (0.50) | HCRTR1HCRTR2CYP3A4 | |
| Hydrochloric Acid SCHEMBL26643055 | 0.85 | HCRTR2 (0.50) | HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL13733737 | 0.81 | HCRTR2 (0.49) | HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL23018148 | 0.74 | HCRTR2 (0.58) | HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL17501828 | 0.72 | ALDH1A1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL17501812 | 0.71 | HCRTR2 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL27854226 | 0.71 | HCRTR1 (0.52) | HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL17501820 | 0.71 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL26643081 | 0.71 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL2358754 | 0.70 | HCRTR2 (0.64) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218023-A1 | THIAZOLOARYL-METHYL SUBSTITUTED CYCLIC HYDRAZINE-N-CARBOXAMIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-11-16 | — | — | WO | disclosed |