Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GPR3 | P46089 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418278 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10MAPTCYP3A4KMT2A | |
| SCHEMBL2680080 | 0.77 | KMT2A (0.64) | ALDH1A1HSD17B10MAPTPSMB8CYP3A4 | |
| 2-Mercaptobenzimidazole SCHEMBL29360590 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTPSMB8CYP3A4 | |
| 2-Mercaptobenzimidazole SCHEMBL705730 | 0.75 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAPTPSMB8CYP3A4 | |
| SCHEMBL29446348 | 0.74 | KDM4E (0.63) | ALDH1A1HSD17B10MAPTPSMB8CYP3A4 | |
| SCHEMBL2517723 | 0.74 | KDM4E (0.63) | ALDH1A1HSD17B10MAPTKMT2AGPR3 | |
| SCHEMBL30644718 | 0.74 | KDM4E (0.63) | ALDH1A1HSD17B10MAPTKMT2AGPR3 | |
| SCHEMBL1342985 | 0.74 | KDM4E (0.63) | ALDH1A1HSD17B10MAPTPSMB8CYP3A4 | |
| 2-Mercaptobenzimidazole SCHEMBL29562524 | 0.73 | ALDH1A1 (0.94) | ALDH1A1HSD17B10MAPTPSMB8CYP3A4 | |
| SCHEMBL29814291 | 0.69 | ALDH1A1 (0.68) | ALDH1A1HSD17B10MAPTPSMB8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787783-B2 | Heparanase inhibitors and use thereof | Beta Therapeutics Pty Ltd (AU) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787783-B2 | Heparanase inhibitors and use thereof | HPSE, HEXD, ENGASE | ALDH1A1 1394/4885HSD17B10 1091/4885MAPT 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.