Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | GPR3 | P46089 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444778 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GPR3HSD17B10KDM4EAHR | |
| SCHEMBL30644718 | 0.77 | KDM4E (0.63) | ALDH1A1GPR3HSD17B10KDM4EAHR | |
| SCHEMBL11142745 | 0.77 | PARP1 (0.63) | ALDH1A1GPR3HSD17B10KDM4ELMNA | |
| SCHEMBL30644752 | 0.77 | ALDH1A1 (0.58) | ALDH1A1GPR3HSD17B10KDM4EAHR | |
| SCHEMBL2517723 | 0.77 | KDM4E (0.63) | ALDH1A1GPR3HSD17B10KDM4EAHR | |
| SCHEMBL7169724 | 0.76 | ALDH1A1 (0.50) | ALDH1A1GPR3HSD17B10KDM4EAHR | |
| Iodide SCHEMBL11713121 | 0.76 | ALDH1A1 (0.48) | ALDH1A1GPR3HSD17B10KDM4EAHR | |
| Bromide SCHEMBL11714912 | 0.76 | ALDH1A1 (0.48) | ALDH1A1GPR3HSD17B10KDM4EAHR | |
| Aminacrine SCHEMBL1040669 | 0.72 | ALDH1A1 (0.68) | ALDH1A1GPR3HSD17B10KDM4EAHR | |
| Carbazole SCHEMBL28126942 | 0.71 | ALDH1A1 (0.88) | ALDH1A1GPR3HSD17B10KDM4EAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373268-B1 | METHOD FOR THE MANUFACTURE OF ANAGRELIDE | SHIRE US INC (US) | 2008-06-04 | — | — | EP | claimed |
| EP-1626047-B1 | PROCESS FOR PRODUCING SUBSTITUTED AMINOQUINAZOLINONE DERIVATIVE AS A PEST CONTROL AGENT | NIHON NOHYAKU CO LTD (JP) | 2010-12-08 | — | — | EP | disclosed |
| EP-1626047-A4 | PROCESS FOR PRODUCING SUBSTITUTED AMINOQUINAZOLINONE DERIVATIVE, INTERMEDIATE THEREFOR, AND PEST CONTROL AGENT | NIHON NOHYAKU CO LTD (JP) | 2008-12-03 | — | — | EP | disclosed |
| WO-2004099184-A1 | PROCESS FOR PRODUCING SUBSTITUTED AMINOQUINAZOLINONE DERIVATIVE, INTERMEDIATE THEREFOR, AND PEST CONTROL AGENT | NIHON NOHYAKU CO., LTD. (JP) | 2004-11-18 | — | — | WO | disclosed |