SCHEMBL30644773

SCHEMBL30644773

Fc1ccc(F)c(-c2c3nc(c(-c4c(F)ccc(F)c4F)c4ccc([nH]4)c(-c4c(F)ccc(F)c4F)c4nc(c(-c5c(F)ccc(F)c5F)c5ccc2[nH]5)C=C4)C=C3)c1F

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 4/20 0.51
▸ TOP1 P11387 2/20 0.46
▸ CYCS P99999 3/20 0.45
▸ ENPP2 Q13822 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17222195 0.85 TERT (0.47) TERTTOP1CYCSENPP2
SCHEMBL5571177 0.83 TERT (0.49) TERTTOP1CYCSENPP2
SCHEMBL29353372 0.82 TERT (0.47) TERTTOP1CYCSENPP2
SCHEMBL29582816 0.82 TERT (0.47) TERTTOP1CYCSENPP2
SCHEMBL29648942 0.82 TERT (0.47) TERTTOP1CYCSENPP2
SCHEMBL174717 0.82 TERT (0.47) TERTTOP1CYCSENPP2
SCHEMBL17222191 0.82 TERT (0.45) TERTTOP1CYCSENPP2
SCHEMBL2895629 0.81 TERT (0.46) TERTTOP1CYCSENPP2
SCHEMBL1313020 0.81 TERT (0.46) TERTTOP1CYCSENPP2
SCHEMBL4020034 0.81 TERT (0.46) TERTTOP1CYCSENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4529622-A1 METHOD FOR MAKING HEVL-FILTERING CONTACT LENSES Alcon Inc. (CH) 2025-04-02 — — EP claimed
WO-2023228054-A1 METHOD FOR MAKING HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 — — WO claimed
US-20230374225-A1 METHOD FOR MAKING HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 — — US claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 — — US disclosed
EP-4529622-A1 METHOD FOR MAKING HEVL-FILTERING CONTACT LENSES Alcon Inc. (CH) 2025-04-02 — — EP disclosed
CN-119137510-A UV/HEVL filtering contact lenses 爱尔康公司 2024-12-13 — — CN disclosed
WO-2023228054-A1 METHOD FOR MAKING HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-30 — — WO disclosed
US-20230374225-A1 METHOD FOR MAKING HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 — — US disclosed
US-20230374306-A1 UV/HEVL-FILTERING CONTACT LENSES ALCON INC. (CH) 2023-11-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L TERT 573/4885TOP1 2294/4885CYCS 4048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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