Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5549820 | 0.83 | MAPT (0.54) | KMT2AALDH1A1CES2 | |
| SCHEMBL27483949 | 0.83 | CES2 (0.55) | KMT2ASMN1; SMN2MEN1POLBALDH1A1 | |
| SCHEMBL8227131 | 0.83 | MEN1 (0.50) | KMT2ASMN1; SMN2MEN1POLBALDH1A1 | |
| SCHEMBL1760202 | 0.82 | AKR1C3 (0.66) | SMN1; SMN2ALDH1A1CYP3A4CES2NPSR1 | |
| SCHEMBL1993610 | 0.82 | AKR1C3 (0.66) | SMN1; SMN2ALDH1A1CYP3A4CES2NPSR1 | |
| SCHEMBL15947806 | 0.81 | ALDH1A1 (0.46) | KMT2ASMN1; SMN2MEN1POLBALDH1A1 | |
| SCHEMBL15947827 | 0.81 | PTGS1 (0.56) | KMT2ASMN1; SMN2MEN1POLBALDH1A1 | |
| SCHEMBL377074 | 0.81 | AURKA (0.57) | CES2NPSR1AKR1C3AKR1C2ACP3 | |
| SCHEMBL6685970 | 0.81 | KDM4E (0.49) | KMT2ASMN1; SMN2MEN1POLBALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL29072753 | 0.79 | MEN1 (0.49) | KMT2ASMN1; SMN2MEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111344281-B | Potassium channel inhibitors substituted benzimidazoles | 阿塞西翁制药公司 | 2023-11-14 | — | — | CN | disclosed |