Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACA | Q13085 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914534 | 0.71 | ALDH1A1 (0.41) | ACACAPOLBBLMTDP1MEN1 | |
| SCHEMBL30412517 | 0.71 | BRD4 (0.40) | POLBBLMTDP1KMT2AMAPT | |
| SCHEMBL2798360 | 0.70 | MEN1 (0.47) | POLBBLMTDP1MEN1KMT2A | |
| SCHEMBL1815388 | 0.69 | ALDH1A1 (0.45) | POLBMAPTPDK2KDM4EALDH1A1 | |
| SCHEMBL19520606 | 0.69 | HPGD (0.53) | POLBMEN1KMT2AMAPTRAB9A | |
| SCHEMBL1818582 | 0.69 | LMNA (0.50) | POLBMEN1KMT2AMAPTRAB9A | |
| SCHEMBL10506137 | 0.69 | MEN1 (0.58) | POLBBLMTDP1MEN1KMT2A | |
| SCHEMBL18006591 | 0.69 | MCL1 (0.42) | POLBTDP1MAPTRAB9AKDM4E | |
| SCHEMBL1662603 | 0.69 | PPARG (0.44) | MEN1KMT2AMAPTPDK2KDM4E | |
| SCHEMBL15206311 | 0.67 | KDM4E (0.45) | POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025031383-A1 | BIFUNCTIONAL LINKER COMPOUND, ANTIBODY DRUG CONJUGATE, PREPARATION METHOD FOR ANTIBODY DRUG CONJUGATE, AND USE OF ANTIBODY DRUG CONJUGATE | 杭州爱科瑞思生物医药有限公司 | 2025-02-13 | — | — | WO | disclosed |
| CN-117069793-A | Bifunctional linker compound, antibody drug conjugate, and preparation methods and applications thereof | 杭州爱科瑞思生物医药有限公司 | 2023-11-17 | — | — | CN | disclosed |