Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18794840 | 0.83 | PDK2 (0.46) | ALDH1A1KDM4EPDK2SCN9AL3MBTL1 | |
| SCHEMBL9205693 | 0.81 | WDR5 (0.70) | ALDH1A1KDM4EGAAWDR5POLB | |
| SCHEMBL12297764 | 0.81 | SOD1 (0.46) | MRGPRX4OGG1MAPTSOD1CYP2C19 | |
| SCHEMBL5274567 | 0.81 | ALOX15 (0.54) | ALDH1A1KDM4EMRGPRX4MAPT | |
| SCHEMBL8149163 | 0.79 | MAPT (0.46) | ALDH1A1KDM4EMRGPRX4OGG1MAPT | |
| SCHEMBL7846467 | 0.79 | WDR5 (0.44) | ALDH1A1GAAWDR5MRGPRX4OGG1 | |
| SCHEMBL1816835 | 0.79 | SMN1; SMN2 (0.58) | ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL13755090 | 0.79 | OGG1 (0.46) | ALDH1A1KDM4EPDK2OGG1MAPT | |
| SCHEMBL6462111 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KDM4EGLAGAAMAPT | |
| SCHEMBL3914534 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4EPDK2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947712-B2 | Antiarthritic agents; asthma; chronic obstructive pulminary diosrders; atherosclerosis; vision defects; hepatitis; central nervous system disorders; cardiovascular disorders; wound healing agents; restenosis; cirrhosis; multiple sclerosis; glomerulonephritis; graft versus host disease; antidiabetic agent | WYETH LLC (US) | 2011-05-24 | — | — | US | disclosed |