Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 2/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | GRK5 | P34947 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087688 | 1.00 | CLPP (0.44) | CLPPS1PR5S1PR1GRK5CDK8 | |
| SCHEMBL29087684 | 1.00 | CLPP (0.44) | CLPPS1PR5S1PR1GRK5CDK8 | |
| SCHEMBL30646813 | 0.91 | L3MBTL1 (0.48) | CLPPS1PR5S1PR1GRK5CDK8 | |
| SCHEMBL29087771 | 0.91 | L3MBTL1 (0.48) | CLPPS1PR5S1PR1GRK5CDK8 | |
| SCHEMBL29087769 | 0.91 | L3MBTL1 (0.48) | CLPPS1PR5S1PR1GRK5CDK8 | |
| SCHEMBL29087725 | 0.88 | USP2 (0.45) | CCR2CHRM4HIF1AEPAS1FAAH | |
| SCHEMBL30646800 | 0.88 | USP2 (0.45) | CCR2CHRM4HIF1AEPAS1FAAH | |
| SCHEMBL29087728 | 0.88 | USP2 (0.45) | CCR2CHRM4HIF1AEPAS1FAAH | |
| SCHEMBL29617602 | 0.88 | S1PR5 (0.52) | S1PR5S1PR1GRK5CDK8PDGFRA | |
| SCHEMBL29617625 | 0.88 | CLPP (0.41) | CLPPS1PR5S1PR1GRK5CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710431-A | Small molecule compounds and compositions | 泰洛治疗公司 | 2023-09-05 | — | — | CN | disclosed |