Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29087745 | 1.00 | CLPP (0.41) | CLPPELANEDRD3DRD2CYP2C9 | |
| SCHEMBL29087757 | 1.00 | CLPP (0.41) | CLPPELANEDRD3DRD2CYP2C9 | |
| SCHEMBL29087702 | 0.88 | PAX8 (0.44) | S1PR5S1PR1PDGFRAALDH1A1KDM4E | |
| SCHEMBL29087704 | 0.88 | PAX8 (0.44) | S1PR5S1PR1PDGFRAALDH1A1KDM4E | |
| SCHEMBL29087688 | 0.88 | CLPP (0.44) | CLPPDRD3DRD2S1PR5S1PR1 | |
| SCHEMBL30646802 | 0.88 | CLPP (0.44) | CLPPDRD3DRD2S1PR5S1PR1 | |
| SCHEMBL29087684 | 0.88 | CLPP (0.44) | CLPPDRD3DRD2S1PR5S1PR1 | |
| SCHEMBL29617611 | 0.82 | ALDH1A1 (0.39) | S1PR5S1PR1ALDH1A1KDM4EPPARG | |
| SCHEMBL29087746 | 0.82 | ALDH1A1 (0.39) | S1PR5S1PR1ALDH1A1KDM4EPPARG | |
| SCHEMBL29087749 | 0.82 | ALDH1A1 (0.39) | S1PR5S1PR1ALDH1A1KDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4247374-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | Telo Therapeutics, Inc. (US) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022109209-A1 | SMALL MOLECULE COMPOUNDS AND COMPOSITIONS | TELO THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |