SCHEMBL3064686

SCHEMBL3064686

O=C(O)/C=C\C(=O)NCCS

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
TAAR1 Q96RJ0 6/20 0.52
LMNA P02545 2/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.41
EGLN1 Q9GZT9 1/20 0.41
EGLN3 Q9H6Z9 1/20 0.41
GAA P10253 2/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4879990 1.00 ALDH1A1 (0.52) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL4879984 0.91 TAAR1 (0.39) ALDH1A1TAAR1KMT2APOLB
SCHEMBL7155993 0.87 ALDH1A1 (0.56) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL7155998 0.87 ALDH1A1 (0.56) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL10578482 0.85 ALDH1A1 (0.59) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL10578491 0.85 ALDH1A1 (0.59) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL8413411 0.82 ALDH1A1 (0.38) ALDH1A1TAAR1KMT2A
SCHEMBL8415075 0.82 ALDH1A1 (0.38) ALDH1A1TAAR1KMT2A
SCHEMBL11133917 0.81 ALDH1A1 (0.63) ALDH1A1TAAR1LMNACYP2D6CYP2C19
SCHEMBL11133921 0.81 ALDH1A1 (0.63) ALDH1A1TAAR1LMNACYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0465342-B1 REDUCING COSMETIC COMPOSITION FOR PERMING CONTAINING A DERIVATIVE OF A N-(MERCAPTO-ALKYL)SUCCINAMIC ACID OR A N-(MERCAPTO-ALKYL)SUCCINIMID AND ITS USE IN A PROCESS FOR PERMANENT HAIR SHAPING L'OREAL (FR) 1993-09-29 EP claimed
EP-3296327-B1 METHOD FOR PRODUCING ELLIPTICAL, NEEDLE-SHAPED, OR ROD-SHAPED POLYMER PARTICLES NISSHINBO HOLDINGS INC (JP) 2024-05-15 EP disclosed
US-10729623-B2 Method for producing elliptical, needle-shaped, or rod-shaped polymer particles NISSHINBO HOLDINGS, INC. (JP) 2020-08-04 US disclosed
US-10584193-B2 Flat elliptical polymer particles, and use thereof NISSHINBO HOLDINGS INC. (JP) 2020-03-10 US disclosed
WO-2019216126-A1 PRODUCTION METHOD FOR DISC-SHAPED POLYMER PARTICLES 日清紡ホールディングス株式会社 (JP) 2019-11-14 WO disclosed
EP-3536308-A1 SKIN CARE PREPARATIONS Nisshinbo Holdings Inc. (JP) 2019-09-11 EP disclosed
US-20190254938-A1 SKIN COSMETICS NISSHINBO HOLDINGS INC. (JP) 2019-08-22 US disclosed
EP-3070138-B1 ULTRAVIOLET SCATTERING AGENT AND APPLICATION THEREFOR NISSHINBO HOLDINGS INC (JP) 2019-01-02 EP disclosed
US-20180134823-A1 FLAT ELLIPTICAL POLYMER PARTICLES, AND USE THEREOF NISSHINBO HOLDINGS INC. (JP) 2018-05-17 US disclosed
US-20180118867-A1 ELLIPTICAL, NEEDLE-SHAPED, OR ROD-SHAPED CROSSLINKED POLYMER PARTICLES, AND USE THEREOF NISSHINBO HOLDINGS INC. (JP) 2018-05-03 US disclosed
EP-1553124-A1 FLAKY PARTICLES AND PROCESS FOR PRODUCTION THEREOF Nisshinbo Industries, Inc. (JP) 2005-07-13 EP disclosed
US-20050118424-A1 particles comprising thermoplastic resins impregnated with carbodiimide compounds, having heat and solvent resistance, used as curing agents, stabilizers, hardeners, adhesives, coatings, paints, reinforcements and in automobiles, electronics, furniture, construction materials and as spacers TAKAHASHI IKUO (JP) 2005-06-02 US disclosed
EP-1528077-A1 COMPOSITE PARTICLE HAVING CARBODIIMIDE RESIN LAYER AND PROCESS FOR PRODUCING THE SAME Nisshinbo Industries, Inc. (JP) 2005-05-04 EP disclosed
US-6866934-B2 A thermoplastic resin having a functional group and carbodiimide compound impregnated only in the surface layer section or both surface layer section and inside the base particle and both are strongly bonded by crosslinking reaction NISSHINBO INDUSTRIES, INC. (JP) 2005-03-15 US disclosed
US-20030215636-A1 A thermoplastic resin having a functional group and carbodiimide compound impregnated only in the surface layer section or both surface layer section and inside the base particle and both are strongly bonded by crosslinking reaction NISSHINBO INDUSTRIES, INC. (JP) 2003-11-20 US disclosed
EP-1344795-A2 Carbodiimide-containing hardening type reactive particles, process for producing the same, and use of the same NISSHINBO INDUSTRIES, INC. (JP) 2003-09-17 EP disclosed
US-6534659-B2 Amidation of an acid anhydride by a compound comprising a nitrogen/sulfur saturated ring, e.g., thiazolidine; odorless corrosion inhibitors for metal; pollution control NIPPON SHOKUBAI CO., LTD. (JP) 2003-03-18 US disclosed
US-20010047096-A1 Amidation of an acid anhydride by a compound comprising a nitrogen/sulfur saturated ring, e.g., thiazolidine; odorless corrosion inhibitors for metal; pollution control NIPPON SHOKUBAI CO., LTD. (JP) 2001-11-29 US disclosed
EP-1149833-A1 Sulfidoamidocarboxylic acids used as corrosion inhibitors Nippon Shokubai Co., Ltd. (JP) 2001-10-31 EP disclosed
US-5154918-A COSMETIC COMPOSITION FOR USE IN PERMANENT DEFORMATION OF HAIR CONTAINS AS A REDUCING AGENT A DERIVATIVE OF N-(MERCAPTO ALKYL) SUCCINAMIC ACID OR OF N-(MERCAPTO ALKYL) SUCCINIMIDE L'OREAL (FR) 1992-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010047096-A1 Amidation of an acid anhydride by a compound comprising a nitrogen/sulfur saturated ring, e.g., thiazolidine; odorless corrosion inhibitors for metal; pollution control CTH, TST, SLC7A11 ALDH1A1 1774/4885TAAR1 1898/4885LMNA 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.