Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2810527 | 0.84 | NPSR1 (0.55) | NPSR1L3MBTL1HSP90AA1KMT2AMEN1 | |
| SCHEMBL14622022 | 0.82 | APOBEC3A (0.46) | NPSR1L3MBTL1HSP90AA1KMT2AMEN1 | |
| Fluoride Ion SCHEMBL5148030 | 0.81 | NPSR1 (0.55) | NPSR1L3MBTL1HSP90AA1KMT2AMEN1 | |
| Bromide SCHEMBL5150406 | 0.81 | NPSR1 (0.55) | NPSR1L3MBTL1HSP90AA1KMT2AMEN1 | |
| SCHEMBL16674216 | 0.79 | NPSR1 (0.65) | NPSR1L3MBTL1HSP90AA1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3072623 | 0.78 | HSP90AA1 (0.64) | NPSR1L3MBTL1HSP90AA1KMT2AMEN1 | |
| SCHEMBL10918992 | 0.78 | L3MBTL1 (0.63) | NPSR1L3MBTL1HSP90AA1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3062156 | 0.77 | NPSR1 (0.58) | NPSR1L3MBTL1HSP90AA1KMT2AMEN1 | |
| SCHEMBL9811156 | 0.76 | L3MBTL1 (0.61) | NPSR1L3MBTL1HSP90AA1KMT2AMEN1 | |
| SCHEMBL5430523 | 0.76 | MAPT (0.63) | NPSR1L3MBTL1HSP90AA1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123963-A2 | UTILIZING ELECTROMAGNETIC RADIATION TO ACTIVATE FILTERCAKE BREAKERS DOWNHOLE | HORTON AMY C (US) | 2010-10-28 | — | — | WO | claimed |
| US-20100263867-A1 | UTILIZING ELECTROMAGNETIC RADIATION TO ACTIVATE FILTERCAKE BREAKERS DOWNHOLE | HORTON AMY C | 2010-10-21 | — | — | US | claimed |
| WO-2010123963-A2 | UTILIZING ELECTROMAGNETIC RADIATION TO ACTIVATE FILTERCAKE BREAKERS DOWNHOLE | HORTON AMY C (US) | 2010-10-28 | — | — | WO | disclosed |
| US-20100263867-A1 | UTILIZING ELECTROMAGNETIC RADIATION TO ACTIVATE FILTERCAKE BREAKERS DOWNHOLE | HORTON AMY C | 2010-10-21 | — | — | US | disclosed |