SCHEMBL30647311

SCHEMBL30647311

C[C@@H](OC(C)(C)C)[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)NOC(C)(C)C)NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](Cc1cn(C(=O)OC(C)(C)C)cn1)NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 7/20 0.32
▸ OPRD1 P41143 6/20 0.32
▸ CCKBR P32239 5/20 0.32
▸ CCKAR P32238 5/20 0.32
▸ BCHE P06276 1/20 0.31
▸ ACHE P22303 1/20 0.31
▸ CTSS P25774 1/20 0.30
▸ CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29554598 0.92 REN (0.37) RENOPRD1CCKBRCCKARCTSS
SCHEMBL31088668 0.90 REN (0.36) RENOPRD1CCKBRCCKARCTSS
SCHEMBL29555524 0.86 OPRD1 (0.41) RENOPRD1CCKBRCCKAR
SCHEMBL30096878 0.82 REN (0.37) RENOPRD1CCKBRCCKARCTSS
SCHEMBL31094172 0.81 NMBR (0.38) RENBCHEACHE
SCHEMBL29555339 0.81 OPRM1 (0.39) OPRD1CCKBRCCKAR
SCHEMBL29824489 0.80 OPRD1 (0.37) RENOPRD1CCKBRCCKAR
SCHEMBL34463366 0.79 REN (0.38) RENOPRD1CCKBRCCKAR
SCHEMBL30437952 0.79 REN (0.40) RENOPRD1CCKBRCCKAR
SCHEMBL30836804 0.78 REN (0.42) RENOPRD1CCKBRCCKAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230364194-A1 GLP-1R/GCGR Dual Target Agonist Polypeptide Derivative for Treatment of Hepatic Fibrosis Associated with Viral Hepatitis SHENZHEN TURIER BIOTECH CO., LTD. (CN) 2023-11-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230364194-A1 GLP-1R/GCGR Dual Target Agonist Polypeptide Derivative for Treatment of Hepatic Fibrosis Associated with Viral Hepatitis GLP1R, GCGR, GIPR REN 713/4885OPRD1 2819/4885CCKBR 18/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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