Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680567 | 0.77 | CRBN (0.53) | NPC1RAB9APDE3BPDE3AMAPT | |
| SCHEMBL30648385 | 0.76 | CYP11B1 (0.40) | EPHX2HTTALDH1A1LMNAKMT2A | |
| SCHEMBL4258367 | 0.75 | HTT (0.59) | EPHX2HTTALDH1A1LMNAKMT2A | |
| SCHEMBL13680572 | 0.75 | GRIA1 (0.62) | HTTALDH1A1CYP11B1CYP11B2NPC1 | |
| SCHEMBL434490 | 0.73 | EPHX2 (0.77) | EPHX2HTTALDH1A1LMNAKMT2A | |
| SCHEMBL30648382 | 0.71 | CYP11B1 (0.44) | EPHX2HTTALDH1A1LMNACYP11B1 | |
| SCHEMBL30648398 | 0.69 | KIF11 (0.46) | EPHX2HTTALDH1A1LMNAKMT2A | |
| SCHEMBL21400777 | 0.69 | HTT (0.55) | EPHX2HTTALDH1A1LMNAKMT2A | |
| SCHEMBL9732854 | 0.68 | PDE3B (0.82) | EPHX2HTTALDH1A1LMNACYP11B1 | |
| SCHEMBL4142652 | 0.68 | PDE3B (0.52) | EPHX2HTTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947846-B | Parallel ring derivative and preparation method and application thereof | 成都硕德药业有限公司 | 2026-02-27 | — | — | CN | disclosed |
| CN-116947846-A | Parallel ring derivative and preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2023-10-27 | — | — | CN | disclosed |