Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30648377 | 0.76 | EPHX2 (0.47) | CYP11B1CYP11B2HTTALDH1A1LMNA | |
| SCHEMBL22528207 | 0.69 | SLC6A2 (0.42) | FFAR4SLC6A2SLC6A4KCNH2KMO | |
| SCHEMBL4258367 | 0.67 | HTT (0.59) | CYP11B1CYP11B2HTTALDH1A1LMNA | |
| SCHEMBL30648382 | 0.64 | CYP11B1 (0.44) | CYP11B1CYP11B2HTTALDH1A1LMNA | |
| SCHEMBL30648408 | 0.63 | ABL1 (0.39) | CYP11B1CYP11B2MAOAMAOB | |
| SCHEMBL30648390 | 0.63 | ALDH1A1 (0.44) | CYP11B1CYP11B2HTTALDH1A1LMNA | |
| SCHEMBL30648398 | 0.62 | KIF11 (0.46) | CYP11B1CYP11B2HTTALDH1A1LMNA | |
| SCHEMBL9732854 | 0.62 | PDE3B (0.82) | CYP11B1CYP11B2HTTALDH1A1LMNA | |
| SCHEMBL4748346 | 0.61 | DHFR (0.46) | CYP11B1CYP11B2HTTALDH1A1LMNA | |
| SCHEMBL23967054 | 0.60 | SLC6A2 (0.34) | SLC6A2SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947846-B | Parallel ring derivative and preparation method and application thereof | 成都硕德药业有限公司 | 2026-02-27 | — | — | CN | disclosed |
| CN-116947846-A | Parallel ring derivative and preparation method and application thereof | 成都苑东生物制药股份有限公司 | 2023-10-27 | — | — | CN | disclosed |