SCHEMBL30648498

SCHEMBL30648498

COc1c(-c2cccs2)ccc(P(C)C)c1P(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.40
RPS6KB2 Q9UBS0 2/20 0.38
SMN1; SMN2 Q16637 5/20 0.35
ALDH1A1 P00352 3/20 0.35
GAA P10253 3/20 0.35
KDM4E B2RXH2 2/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
PDE4C Q08493 1/20 0.35
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
MAOB P27338 3/20 0.34
MAPT P10636 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HTT P42858 1/20 0.34
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
TUBB4A P04350 2/20 0.34
TUBB P07437 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18133657 0.80 ERN1 (0.50) ERN1RPS6KB2SMN1; SMN2ALDH1A1GAA
SCHEMBL7214449 0.75 ERN1 (0.46) ERN1RPS6KB2SMN1; SMN2ALDH1A1GAA
SCHEMBL27601843 0.72 ERN1 (0.55) ERN1RPS6KB2SMN1; SMN2ALDH1A1GAA
SCHEMBL28672054 0.69 SMN1; SMN2 (0.49) ERN1RPS6KB2SMN1; SMN2ALDH1A1GAA
SCHEMBL8864220 0.68 ALDH1A1 (0.44) ERN1RPS6KB2SMN1; SMN2ALDH1A1GAA
SCHEMBL6067986 0.67 ERN1 (0.52) ERN1RPS6KB2SMN1; SMN2ALDH1A1GAA
SCHEMBL18032697 0.66 DPP4 (0.50) ERN1RPS6KB2SMN1; SMN2ALDH1A1GAA
SCHEMBL7213105 0.65 ERN1 (0.58) ERN1RPS6KB2SMN1; SMN2ALDH1A1GAA
SCHEMBL26259793 0.65 IDO1 (0.46) RPS6KB2SMN1; SMN2ALDH1A1GAAKDM4E
SCHEMBL7212822 0.65 RPS6KB2 (0.49) ERN1RPS6KB2SMN1; SMN2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116948065-A Solid catalyst component for olefin polymerization, preparation method thereof and catalyst containing solid catalyst component 中国石油天然气股份有限公司 2023-10-27 CN claimed
CN-116948065-A Solid catalyst component for olefin polymerization, preparation method thereof and catalyst containing solid catalyst component 中国石油天然气股份有限公司 2023-10-27 CN disclosed