SCHEMBL7214449

SCHEMBL7214449

COc1c(-c2cccs2)ccc2c(OC)c(-c3cccs3)ccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.46
IDO1 P14902 1/20 0.42
TDO2 P48775 1/20 0.42
SMN1; SMN2 Q16637 5/20 0.41
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPK1 P28482 1/20 0.41
TUBB4A P04350 4/20 0.41
TUBB P07437 4/20 0.41
TUBA3C P0DPH7 4/20 0.41
TUBA1B P68363 4/20 0.41
TUBA4A P68366 4/20 0.41
TUBB4B P68371 4/20 0.41
TUBB3 Q13509 4/20 0.41
TUBB2A Q13885 4/20 0.41
TUBB8 Q3ZCM7 4/20 0.41
TUBA3E Q6PEY2 4/20 0.41
TUBA1A Q71U36 4/20 0.41
TUBA1C Q9BQE3 4/20 0.41
TUBB6 Q9BUF5 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18133657 0.90 ERN1 (0.50) ERN1IDO1TDO2SMN1; SMN2ALDH1A1
SCHEMBL18032697 0.88 DPP4 (0.50) ERN1IDO1TDO2SMN1; SMN2ALDH1A1
SCHEMBL26259793 0.83 IDO1 (0.46) IDO1TDO2SMN1; SMN2ALDH1A1KDM4E
SCHEMBL27601843 0.81 ERN1 (0.55) ERN1IDO1TDO2SMN1; SMN2ALDH1A1
SCHEMBL28672054 0.78 SMN1; SMN2 (0.49) ERN1IDO1TDO2SMN1; SMN2ALDH1A1
SCHEMBL6067986 0.75 ERN1 (0.52) ERN1IDO1TDO2SMN1; SMN2ALDH1A1
SCHEMBL30648498 0.75 ERN1 (0.40) ERN1IDO1TDO2SMN1; SMN2ALDH1A1
SCHEMBL26259776 0.74 LTA4H (0.42) ERN1TDO2SMN1; SMN2ALDH1A1KDM4E
SCHEMBL7213105 0.73 ERN1 (0.58) ERN1IDO1TDO2SMN1; SMN2ALDH1A1
SCHEMBL7212822 0.73 RPS6KB2 (0.49) ERN1IDO1TDO2SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6617462-B1 Di- and tetra-methoxy-bis(2-thienyl)naphthalene monomers that can be electropolymerized to form conductive polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2003-09-09 US claimed
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed
US-6617462-B1 Di- and tetra-methoxy-bis(2-thienyl)naphthalene monomers that can be electropolymerized to form conductive polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2003-09-09 US disclosed
US-6359149-B1 Bithienylnaphthalene- and bis(3,4-ethylenedioxythienyl)naphthalene-based monomers and polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2002-03-19 US disclosed
US-6291621-B1 FOR PRODUCING THIN FILMS AND COATINGS USEFUL IN ELECTROCHROMIC APPLICATIONS; ELECTROCONDUCTIVITY, ELECTRODES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2001-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND NUDC, CCNL2, SPIN3 ERN1 2995/4885IDO1 1470/4885TDO2 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.