Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063527 | 0.88 | CTSS (0.36) | SRCBRAFKDRAADATADORA3 | |
| SCHEMBL3056461 | 0.85 | HTR2A (0.40) | SRCBRAFKDRAADATADORA3 | |
| SCHEMBL3061674 | 0.73 | PDE10A (0.38) | SRCBRAFKDRAADATADORA3 | |
| SCHEMBL3064869 | 0.73 | NPC1 (0.41) | ADORA3PTGS2CA12CA1CA2 | |
| SCHEMBL3662000 | 0.71 | CTSS (0.36) | SRCBRAFKDRAADATADORA3 | |
| SCHEMBL28816224 | 0.70 | NOTUM (0.45) | SRCBRAFKDRAADATADORA3 | |
| SCHEMBL3057381 | 0.66 | NPBWR1 (0.40) | HTR2AHTR2CTDP2NPBWR1MCHR1 | |
| SCHEMBL17970897 | 0.63 | ATM (0.51) | SRCBRAFKDRAADATADORA3 | |
| SCHEMBL20956637 | 0.63 | MEN1 (0.55) | SRCKDRHTR2AXDH | |
| SCHEMBL919079 | 0.62 | BRD9 (0.34) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225211-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | DU PONT (US) | 2013-10-02 | — | — | EP | disclosed |
| US-20100267561-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY | 2010-10-21 | — | — | US | disclosed |
| EP-2225211-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009086041-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267561-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | CYP1A1, CYP1B1, CBR3 | SRC 2971/4885BRAF 1991/4885KDR 2235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.