Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061674 | 0.89 | PDE10A (0.38) | CTSSSRCKDRAADATBRAF | |
| SCHEMBL3063527 | 0.82 | CTSS (0.36) | CTSSSRCKDRAADATBRAF | |
| SCHEMBL3056461 | 0.78 | HTR2A (0.40) | SRCKDRAADATBRAFITGA4 | |
| SCHEMBL3064875 | 0.71 | SRC (0.35) | SRCKDRAADATBRAFNPBWR1 | |
| SCHEMBL3057381 | 0.70 | NPBWR1 (0.40) | HPGDITGA4ITGB7NPBWR1MCHR1 | |
| SCHEMBL3064869 | 0.68 | NPC1 (0.41) | ITGB1ITGA4ITGB7ADORA3 | |
| SCHEMBL16635022 | 0.66 | NPC1 (0.58) | HPGDADORA1ADORA3 | |
| SCHEMBL17973836 | 0.65 | CTSS (0.47) | CTSSSRCKDRAADATBRAF | |
| SCHEMBL6151773 | 0.64 | NOTUM (0.44) | CTSSSRCKDRAADATBRAF | |
| SCHEMBL14973016 | 0.63 | MAPT (0.46) | BRAFHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225211-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. du Pont de Nemours and Company (US) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009086041-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |