⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809345 | 0.84 | VCP (0.33) | — | |
| SCHEMBL419449 | 0.81 | VCP (0.38) | — | |
| SCHEMBL1808857 | 0.78 | VCP (0.36) | — | |
| SCHEMBL22042201 | 0.77 | MEN1 (0.32) | — | |
| SCHEMBL24834495 | 0.75 | — | — | |
| SCHEMBL1809301 | 0.74 | VCP (0.38) | — | |
| SCHEMBL1378109 | 0.73 | — | — | |
| SCHEMBL27886193 | 0.73 | HSD17B10 (0.32) | — | |
| SCHEMBL6848990 | 0.73 | — | — | |
| SCHEMBL2559194 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984798-B1 | DRUG DELIVERY VIA THERAPEUTIC HYDROGELS | UROTEQ INC (CA) | 2005-10-05 | — | — | EP | claimed |
| US-7858349-B2 | Anti-cancer compounds | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2010-12-28 | — | — | US | disclosed |
| US-20100267078-A1 | Selective Detection of Proteins that Contain Two or More Alpha-Helical Transmembrane Domains | Life Technologies Corporation (US) | 2010-10-21 | — | — | US | disclosed |
| US-20090088454-A1 | ANTI-CANCER COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-04-02 | — | — | US | disclosed |
| US-7427496-B2 | Anti-cancer compounds | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2008-09-23 | — | — | US | disclosed |
| US-20060183772-A1 | To inhibit tumor growth in an animal; to induce apoptosis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-08-17 | — | — | US | disclosed |
| US-20060027455-A1 | Selective detection of proteins that contain two or more alpha-helical transmembrane domains | MOLECULAR PROBES, INC. | 2006-02-09 | — | — | US | disclosed |