SCHEMBL419449

SCHEMBL419449

O=Cc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
VCP P55072 1/20 0.38
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALDH1A1 P00352 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1808857 0.96 VCP (0.36) VCPCA12CA1CA2CA7
SCHEMBL809345 0.96 VCP (0.33) VCPMEN1KMT2AALDH1A1TDP1
SCHEMBL1809301 0.92 VCP (0.38) VCPCA12CA1CA2CA7
SCHEMBL22042201 0.88 MEN1 (0.32) MEN1KMT2AALDH1A1TDP1
SCHEMBL24834495 0.86
SCHEMBL6853641 0.83 VCP (0.33) VCP
SCHEMBL6848990 0.83
SCHEMBL6740109 0.83 VCP (0.30) VCP
SCHEMBL10729785 0.83 CA1 (0.37) VCPCA12CA1CA2CA7
SCHEMBL4274582 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025101667-A1 DIFFUSION BARRIERS TO REDUCE QUEUE-TIME EFFECTS IN EUV LITHOGRAPHY LAM RESEARCH CORPORATION (US) 2025-05-15 WO claimed
CN-119972030-A PFP chromatographic packing, preparation method thereof and application thereof in liquid chromatography 山东第一医科大学(山东省医学科学院) 2025-05-13 CN claimed
CN-119875052-A Ion polymer based on flexible main chain, anion exchange membrane and preparation method thereof 武汉轻工大学 2025-04-25 CN claimed
CN-119775322-A Ruthenium (II) complex fluorescent probe constructed based on Schiff base bridging ligand, and preparation method and application thereof 潍坊科技学院 2025-04-08 CN claimed
CN-118955889-B BODIPY compound, preparation method and application thereof 安徽中医药大学 2025-04-04 CN claimed
CN-116730864-B Supermolecule sensor based on pentafluorophenyl functionalized tetrapod azine, preparation method thereof and application thereof in fluorescence detection of perfluorooctanoic acid 西北师范大学 2025-04-01 CN claimed
CN-119680859-A Poppet valve surface anti-corrosion coating process 上海永疆环境工程有限公司 2025-03-25 CN claimed
CN-119424664-A Tumor microenvironment response pharmaceutical composition and preparation method and application thereof 北京大学 2025-02-14 CN claimed
CN-118955889-A BODIPY compound, preparation method and application thereof 安徽中医药大学 2024-11-15 CN claimed
CN-118955543-A Polypyrrole derivative, preparation method and application 安徽中医药大学 2024-11-15 CN claimed
US-6150378-A 1-((1-HALO-SUBSTITUTEDBENZOYLAMINO)-2-PHENYLETHYL)-CARBONYL -CARBONYLAMINO),2-PHENYL OR PYRID-2-YLSULFAMIDO)ETHANE DERIVATIVES; MUSCULAR DYSTROPHY, NEURODEGENERATION, STROKE, ALZHEIMER'S, AMYOTROPHY, MOTOR NEURON DAMAGE, CNS INJURY CEPHALON, INC. (US) 2000-11-21 US claimed
WO-1999061488-A1 CATALYST SYSTEM TARGOR GMBH (DE) 1999-12-02 WO claimed
WO-1999040129-A1 CATALYST SYSTEM TARGOR GMBH (DE) 1999-08-12 WO claimed
US-5760217-A Porphyrins and their synthesis from dipyrromethanes and aldehydes SUN COMPANY, INC. (US) 1998-06-02 US claimed
EP-0665230-A2 Halocarbyl-substituted porphyrins and their synthesis from meso-halocarbyl-dipyrromethanes and aldehydes SUN COMPANY, INC. (R&M) (US) 1995-08-02 EP claimed
WO-1994025494-A1 RIGID MATERIALS HAVING HIGH SURFACE AREA AND LOW DENSITY ALLIEDSIGNAL INC. (US) 1994-11-10 WO claimed
US-5328939-A Crosslinked nitrogen-containing polymers ALLIEDSIGNAL INC. (US) 1994-07-12 US claimed
US-5322935-A Crosslinking chitosans with anionic salts followed by covalent crosslinkers; high strength, dimensional stability ALLIEDSIGNAL INC. (US) 1994-06-21 US claimed
EP-0349204-A2 Use and regeneration of reagents using coupled reactions and permselective barriers BEND RESEARCH, INC. (US) 1990-01-03 EP claimed
US-4656274-A Polyfluorinated substituted tricyclic quinoline mono and dioxo antifungal agents and process for their preparation ORTHO PHARMACEUTICAL CORPORATION (US) 1987-04-07 US claimed