Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3080515 | 0.97 | MMP12 (0.94) | MMP12MMP13 | |
| SCHEMBL3067782 | 0.97 | MMP12 (0.92) | MMP12MMP13 | |
| SCHEMBL3081316 | 0.97 | MMP12 (1.00) | MMP12MMP13 | |
| SCHEMBL3120626 | 0.97 | MMP12 (1.00) | MMP12MMP13 | |
| SCHEMBL3087294 | 0.96 | MMP12 (0.94) | MMP12MMP13 | |
| SCHEMBL3077621 | 0.96 | MMP12 (0.92) | MMP12MMP13 | |
| SCHEMBL3081870 | 0.93 | MMP12 (1.00) | MMP12MMP13 | |
| SCHEMBL3078733 | 0.93 | MMP12 (0.98) | MMP12MMP13 | |
| SCHEMBL3080467 | 0.92 | MMP12 (0.91) | MMP12MMP13 | |
| SCHEMBL3079221 | 0.89 | MMP12 (1.00) | MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100227859-A1 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH LLC | 2010-09-09 | — | — | US | claimed |
| US-20100227859-A1 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | WYETH LLC | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227859-A1 | TRICYCLIC COMPOUNDS AS MATRIX METALLOPROTEINASE INHIBITORS | MMP13, MMP2, MMP12 | MMP12 3/4885MMP13 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.