SCHEMBL30656003

SCHEMBL30656003

Cc1sc2ccc(OCc3ccccc3F)cc2c1C(=O)N[C@@H](C)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.52
SCN3A Q9NY46 5/20 0.48
PARP15 Q460N3 3/20 0.45
PARP10 Q53GL7 3/20 0.45
MAOB P27338 4/20 0.43
PARP14 Q460N5 1/20 0.43
PTPN1 P18031 5/20 0.41
PTPN2 P17706 3/20 0.41
CDC25B P30305 3/20 0.41
F9 P00740 1/20 0.40
KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656254 1.00 SCN9A (0.52) SCN9ASCN3APARP15PARP10MAOB
SCHEMBL30656154 0.89 SCN9A (0.44) SCN9ASCN3APARP15PARP10MAOB
SCHEMBL30656302 0.89 SCN9A (0.44) SCN9ASCN3APARP15PARP10MAOB
SCHEMBL26661099 0.87 EDNRA (0.52) SCN9AMAOB
SCHEMBL30656189 0.85 SCN9A (0.36) SCN9ASCN3AMAOB
SCHEMBL30656226 0.84 CD38 (0.37) SCN9ASCN3AMAOB
SCHEMBL30656258 0.84 CD38 (0.37) SCN9ASCN3AMAOB
SCHEMBL30656124 0.84 HPGDS (0.37) SCN9ASCN3AMAOB
SCHEMBL26792937 0.83 PARP10 (0.45) SCN9ASCN3APARP15PARP10MAOB
SCHEMBL30656142 0.83 PARP10 (0.43) PARP10MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed