SCHEMBL30656258

SCHEMBL30656258

Cc1sc2ccc(OCc3cccnc3C(F)(F)F)cc2c1C(=O)N[C@@H](C)C(N)=O

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CD38 P28907 1/20 0.37
SCN9A Q15858 3/20 0.36
MAOB P27338 3/20 0.35
FPR2 P25090 1/20 0.34
SCN3A Q9NY46 1/20 0.34
OPRL1 P41146 1/20 0.34
EDNRA P25101 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP3A4 P08684 1/20 0.33
LIMK1 P53667 1/20 0.33
MAOA P21397 1/20 0.33
HPGDS O60760 2/20 0.33
GPR132 Q9UNW8 1/20 0.33
LNPEP Q9UIQ6 1/20 0.32
CTSS P25774 1/20 0.32
CTSK P43235 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656226 1.00 CD38 (0.37) CD38SCN9AMAOBFPR2SCN3A
SCHEMBL30656016 0.90 CD38 (0.36) CD38SCN9AMAOBOPRL1EDNRA
SCHEMBL30656176 0.90 CD38 (0.36) CD38SCN9AMAOBOPRL1EDNRA
SCHEMBL30656189 0.88 SCN9A (0.36) SCN9AMAOBSCN3AEDNRALIMK1
SCHEMBL30656331 0.87 ALDH1A1 (0.38) CD38MAOBOPRL1EDNRAL3MBTL1
SCHEMBL31350334 0.87 CD38 (0.42) CD38MAOBOPRL1EDNRACYP3A4
SCHEMBL30656124 0.86 HPGDS (0.37) SCN9AMAOBSCN3AEDNRAL3MBTL1
SCHEMBL30656180 0.86 HPGDS (0.37) SCN9AMAOBSCN3AEDNRAL3MBTL1
SCHEMBL30655957 0.86 CD38 (0.38) CD38MAOBOPRL1EDNRAL3MBTL1
SCHEMBL30656254 0.84 SCN9A (0.52) SCN9AMAOBSCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed