SCHEMBL30656117

SCHEMBL30656117

CNC(=O)c1c(C)sc2ccc(OCc3scnc3C)cc12

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ICAM1 P05362 1/20 0.36
SELE P16581 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
PPARD Q03181 6/20 0.35
PPARA Q07869 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
EDNRA P25101 1/20 0.34
PPARG P37231 1/20 0.34
FFAR1 O14842 6/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
BACE1 P56817 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
PLK1 P53350 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656161 0.88 EDNRA (0.40) MEN1KMT2APPARDPPARAEDNRA
SCHEMBL26661122 0.88 EDNRA (0.40) MEN1KMT2APPARDPPARAEDNRA
SCHEMBL31350338 0.87 PARP10 (0.39) ICAM1SELEL3MBTL1PPARDPPARA
SCHEMBL30656128 0.86 EGLN2 (0.34) KMT2AL3MBTL1PPARDPPARATDP1
SCHEMBL30656116 0.86 EGLN2 (0.35) L3MBTL1PPARDPPARATDP1EDNRA
SCHEMBL30656070 0.85 ALOX5 (0.41) KMT2A
SCHEMBL30656238 0.85 HPGDS (0.35) KMT2AICAM1SELEL3MBTL1EDNRA
SCHEMBL30656219 0.85 ALDH1A1 (0.34) L3MBTL1PPARDPPARATDP1EDNRA
SCHEMBL30656162 0.85 HPGDS (0.35) KMT2AICAM1SELEL3MBTL1EDNRA
SCHEMBL26792632 0.85 ALDH1A1 (0.34) L3MBTL1PPARDPPARATDP1EDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed