Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1819828 | 0.78 | ALDH1A1 (0.51) | ALDH1A1NPSR1PPARGNCOA2RXFP1 | |
| SCHEMBL811481 | 0.75 | ALDH1A1 (0.78) | ALDH1A1TP53KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL966929 | 0.74 | MAPT (0.74) | ALDH1A1NPSR1PPARGRXFP1KMT2A | |
| SCHEMBL13913676 | 0.73 | RET (0.78) | ALDH1A1NPSR1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL20261927 | 0.73 | ALDH1A1 (0.55) | ALDH1A1NPSR1PPARGNCOA2RXFP1 | |
| SCHEMBL30656125 | 0.72 | KDM4E (0.58) | ALDH1A1NPSR1RXFP1KMT2AKDM4E | |
| SCHEMBL21116532 | 0.72 | ALDH1A1 (0.67) | ALDH1A1NPSR1PPARGRXFP1KMT2A | |
| SCHEMBL1143301 | 0.71 | L3MBTL1 (0.60) | ALDH1A1NPSR1PPARGNCOA2RXFP1 | |
| SCHEMBL12870055 | 0.71 | TERT (0.67) | ALDH1A1NPSR1PPARGNCOA2RXFP1 | |
| SCHEMBL26632993 | 0.71 | RET (0.70) | ALDH1A1NPSR1TP53KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | claimed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | claimed |
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | disclosed |