Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.44 |
| ▸ | RPS27 | P42677 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656267 | 0.80 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL30656058 | 0.80 | ADORA1 (0.46) | KDM4EHSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL30656166 | 0.76 | CNR1 (0.54) | KDM4EALDH1A1GAA | |
| SCHEMBL13514630 | 0.76 | KDM4E (0.40) | KDM4EHSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL27883168 | 0.74 | KDM4E (0.57) | KDM4EHSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL12842048 | 0.73 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL22165383 | 0.72 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL7830973 | 0.72 | ALDH1A1 (0.56) | KDM4EHSD17B10ALDH1A1MAPTLMNA | |
| SCHEMBL30185818 | 0.72 | ALDH1A1 (0.56) | KDM4EHSD17B10ALDH1A1MAPTHPGD | |
| SCHEMBL10371014 | 0.70 | L3MBTL1 (0.55) | KDM4EHSD17B10ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | claimed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | claimed |
| EP-4447962-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023213761-A1 | ADENOSINE 2A RECEPTOR MODULATORS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE DE GENEVE (CH) | 2023-11-09 | — | — | WO | disclosed |