SCHEMBL30656342

SCHEMBL30656342

Cc1sc2ccc(OCc3ccccc3F)cc2c1C(=O)NC1CCNCC1(F)F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 5/20 0.38
PARP15 Q460N3 2/20 0.38
PARP10 Q53GL7 2/20 0.38
ADAM17 P78536 1/20 0.38
SCN3A Q9NY46 7/20 0.37
NTRK1 P04629 1/20 0.36
SSTR4 P31391 1/20 0.36
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
CDC25B P30305 1/20 0.36
SCN1A P35498 1/20 0.36
SCN4A P35499 1/20 0.36
SCN7A Q01118 1/20 0.36
SCN5A Q14524 1/20 0.36
SCN9A Q15858 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN8A Q9UQD0 1/20 0.36
SCN10A Q9Y5Y9 1/20 0.36
MAOB P27338 2/20 0.36
KDM1A O60341 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26661096 1.00 KCNH2 (0.38) KCNH2PARP15PARP10ADAM17SCN3A
SCHEMBL26661131 0.84 SSTR4 (0.36) ADAM17SSTR4
SCHEMBL30656065 0.84 SSTR4 (0.36) ADAM17SSTR4
SCHEMBL24470940 0.84 SLC26A4 (0.49) ADAM17
SCHEMBL26792683 0.84 SSTR4 (0.36) ADAM17SSTR4
SCHEMBL30656145 0.81 APOL1 (0.42) KCNH2PARP15PARP10SCN3ASCN1A
SCHEMBL25301743 0.80 KCNH2 (0.39) KCNH2PARP15PARP10SCN3ANTRK1
SCHEMBL25301961 0.80 SLC26A4 (0.38) KCNH2PARP15PARP10SCN3ANTRK1
SCHEMBL24470920 0.78 SLC26A4 (0.45)
SCHEMBL30656149 0.76 PARP15 (0.41) KCNH2PARP15PARP10SCN3APTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed