SCHEMBL30656149

SCHEMBL30656149

Cc1sc2ccc(OCc3ccccc3F)cc2c1C(=O)NC1(CO)CC1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PARP15 Q460N3 3/20 0.41
PARP10 Q53GL7 3/20 0.41
MAOB P27338 4/20 0.40
PARP14 Q460N5 1/20 0.38
SCN3A Q9NY46 4/20 0.37
PTPN1 P18031 3/20 0.37
PTPN2 P17706 2/20 0.37
CDC25B P30305 2/20 0.37
SCN9A Q15858 1/20 0.37
KCNH2 Q12809 2/20 0.36
RARA P10276 1/20 0.36
RARB P10826 1/20 0.36
RARG P13631 1/20 0.36
GCK P35557 1/20 0.36
MMP1 P03956 1/20 0.36
MMP13 P45452 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30656091 0.96 PARP15 (0.39) PARP15PARP10MAOBPARP14SCN3A
SCHEMBL30656068 0.94 MMP13 (0.42) PARP15PARP10MAOBPARP14SCN3A
SCHEMBL30656182 0.93 MAOB (0.40) PARP15PARP10MAOBPARP14SCN3A
SCHEMBL30656205 0.87 EDNRA (0.46) MAOB
SCHEMBL30656066 0.85 SCN9A (0.35) SCN9AMMP13
SCHEMBL30656112 0.84 CD274 (0.35)
SCHEMBL30656053 0.84 SMO (0.39) PARP10
SCHEMBL30656111 0.83 MMP1 (0.46) PARP15PARP10MAOBPARP14SCN3A
SCHEMBL30656121 0.82 CNR2 (0.38)
SCHEMBL24470582 0.82 SLC26A4 (0.55)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP claimed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN claimed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO claimed
EP-4532013-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2025-04-09 EP disclosed
CN-119421879-A Novel derivatives for the treatment of TRPM3 mediated disorders 勒芬天主教大学 2025-02-11 CN disclosed
WO-2023227697-A1 NEW DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2023-11-30 WO disclosed