Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 17/20 | 1.00 |
| ▸ | PPARG | P37231 | 1/20 | 1.00 |
| ▸ | RARG | P13631 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903924 | 1.00 | RORC (1.00) | RORCPPARGRARG | |
| SCHEMBL12470435 | 0.99 | RORC (0.98) | RORCPPARGRARG | |
| SCHEMBL15566900 | 0.91 | RORC (0.85) | RORCPPARG | |
| SCHEMBL12470433 | 0.90 | RORC (0.81) | RORCPPARGRARG | |
| SCHEMBL11904038 | 0.89 | RORC (1.00) | RORCPPARGRARG | |
| SCHEMBL19840238 | 0.89 | RORC (0.80) | RORCPPARGRARG | |
| SCHEMBL11904117 | 0.88 | RORC (0.79) | RORCPPARGRARG | |
| SCHEMBL12470727 | 0.88 | RORC (0.86) | RORCPPARG | |
| SCHEMBL12471015 | 0.88 | RORC (0.81) | RORCPPARG | |
| SCHEMBL12470446 | 0.88 | RORC (0.79) | RORCPPARGRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250099543-A1 | COMPOSITIONS AND METHODS FOR TREATING INFLAMMATION AND CANCER | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. | 2025-03-27 | — | — | US | disclosed |
| US-20250059154-A1 | CYSTEINE-DEPENDENT INVERSE AGONISTS OF NUCLEAR RECEPTORS ROR-GAMMA/ROR-GAMMA-T AND METHODS OF TREATING DISEASES OR DISORDERS THEREWITH | REATA PHARMACEUTICALS, INC. (US) | 2025-02-20 | — | — | US | disclosed |
| CN-116715676-B | Novel small molecular fluorescent probe for targeting ROR gamma and preparation method and application thereof | 南京中医药大学 | 2024-11-26 | — | — | CN | disclosed |
| US-12109249-B2 | Compositions and methods for treating inflammation and cancer | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION (US) | 2024-10-08 | — | — | US | disclosed |
| US-12060340-B2 | Cysteine-dependent inverse agonists of nuclear receptors ROR-gamma/ROR-gamma-t and methods of treating diseases or disorders therewith | REATA PHARMACEUTICALS, INC (US) | 2024-08-13 | — | — | US | disclosed |
| CN-116715676-A | Novel small molecular fluorescent probe for targeting ROR gamma and preparation method and application thereof | 南京中医药大学 | 2023-09-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12060340-B2 | Cysteine-dependent inverse agonists of nuclear receptors ROR-gamma/ROR-gamma-t and methods of treating diseases or disorders therewith | RORC, RORA, RORB | RORC 1/4885PPARG 17/4885RARG 14/4885 |
| US-20250059154-A1 | CYSTEINE-DEPENDENT INVERSE AGONISTS OF NUCLEAR RECEPTORS ROR-GAMMA/ROR-GAMMA-T AND METHODS OF TREATING DISEASES OR DISORDERS THEREWITH | RORC, RORA, RORB | RORC 1/4885PPARG 17/4885RARG 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.