SCHEMBL30657553

SCHEMBL30657553

CC(=O)c1ccccc1C1=CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.49
CLCN2 P51788 1/20 0.45
ACMSD Q8TDX5 2/20 0.41
CXCR5 P32302 2/20 0.40
GRM2 Q14416 1/20 0.39
ATR Q13535 1/20 0.37
KDM4C Q9H3R0 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
PSMB5 P28074 2/20 0.36
CNR2 P34972 1/20 0.36
F2RL1 P55085 1/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
SERPINE1 P05121 1/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6252397 0.86 PTGS2 (0.48) PTGS2CLCN2ACMSDCXCR5GRM2
SCHEMBL11580876 0.85 CLCN2 (0.55) PTGS2CLCN2ACMSDCXCR5GRM2
SCHEMBL5189366 0.83 BCAT2 (0.49) PTGS2CLCN2ACMSDCXCR5GRM2
SCHEMBL29200125 0.80 CLCN2 (0.45) PTGS2CLCN2ACMSDCXCR5GRM2
SCHEMBL11815728 0.78 PTGS2 (0.59) PTGS2CLCN2ACMSDGRM2TDP1
SCHEMBL188942 0.77 PTGS2 (0.47) PTGS2CLCN2ACMSDGRM2TDP1
SCHEMBL6692972 0.76 PTGS2 (0.46) PTGS2CLCN2GRM2TDP1KDM4E
SCHEMBL20503236 0.76 CLCN2 (0.48) PTGS2CLCN2ACMSDCXCR5GRM2
SCHEMBL29216099 0.76 CLCN2 (0.40) PTGS2CLCN2ACMSDCXCR5GRM2
SCHEMBL7203713 0.75 ACMSD (0.37) PTGS2CLCN2ACMSDGRM2PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117088773-A Synthesis method for forming carbon-carbon bond by palladium catalysis 云南中医药大学 2023-11-21 CN disclosed