Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 5/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26641197 | 0.85 | PLA2G4A (0.44) | SMYD3GRIN2BPLA2G4ANPSR1 | |
| SCHEMBL30657810 | 0.82 | SMN1; SMN2 (0.33) | SMYD3GRIN2BPLA2G4ANPSR1ALPL | |
| SCHEMBL26641151 | 0.81 | KMT2A (0.42) | SMYD3GRM2GRIN2BPLA2G4A | |
| SCHEMBL26798607 | 0.80 | NOTUM (0.47) | — | |
| SCHEMBL6335415 | 0.79 | SMYD3 (0.52) | ADASMYD3GRM2 | |
| SCHEMBL28309917 | 0.77 | ADA (0.46) | ADASMYD3GRM2 | |
| SCHEMBL6335386 | 0.76 | KDM5A (0.46) | ADASMYD3PLA2G4A | |
| SCHEMBL31285216 | 0.76 | GRIN2B (0.36) | GRIN2BNPSR1ALPLPLAA | |
| SCHEMBL28726420 | 0.75 | ADA (0.42) | ADASMYD3GRM2 | |
| SCHEMBL6673526 | 0.73 | ADA (0.44) | ADASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519258-A1 | INHIBITORS OF CDK8 AND CDK19 | University of Dundee (GB) | 2025-03-12 | — | — | EP | disclosed |