Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 7/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781564 | 0.80 | ADA (0.37) | ADACPB2SMYD3 | |
| SCHEMBL6335415 | 0.79 | SMYD3 (0.52) | ADACPB2SMYD3 | |
| SCHEMBL28309917 | 0.77 | ADA (0.46) | ADASMYD3LMNA | |
| SCHEMBL6335386 | 0.76 | KDM5A (0.46) | ADACPB2SMYD3 | |
| SCHEMBL28726420 | 0.75 | ADA (0.42) | ADASMYD3LMNA | |
| SCHEMBL27781554 | 0.73 | CPB2 (0.47) | ADACPB2SMYD3 | |
| SCHEMBL30657808 | 0.73 | ADA (0.38) | ADASMYD3 | |
| SCHEMBL25235849 | 0.72 | CPB2 (0.47) | CPB2SMYD3 | |
| Hydrochloric Acid SCHEMBL28773709 | 0.72 | ADA (0.38) | ADACPB2SMYD3 | |
| SCHEMBL20760647 | 0.72 | ADORA2A (0.37) | CPB2ADORA2AADORA1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478624-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003068743-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-21 | — | — | WO | disclosed |