Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 8/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28726420 | 0.82 | ADA (0.42) | ADASMYD3ADORA3TSHRMC4R | |
| SCHEMBL6335415 | 0.82 | SMYD3 (0.52) | ADASMYD3ADORA3TSHRMC4R | |
| SCHEMBL3689829 | 0.82 | PLA2G4A (0.40) | ADASMYD3TSHRLMNA | |
| SCHEMBL6335386 | 0.79 | KDM5A (0.46) | ADASMYD3 | |
| SCHEMBL24842010 | 0.79 | ADA (0.40) | ADASMYD3GRM2 | |
| SCHEMBL24842794 | 0.79 | ADA (0.40) | ADASMYD3GRM2 | |
| SCHEMBL24841509 | 0.79 | ADA (0.40) | ADASMYD3ADORA3TSHRMC4R | |
| SCHEMBL6673526 | 0.77 | ADA (0.44) | ADASMYD3LMNA | |
| SCHEMBL30657808 | 0.77 | ADA (0.38) | ADASMYD3GRM2 | |
| SCHEMBL27781554 | 0.77 | CPB2 (0.47) | ADASMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110022875-A | Therapeutic inhibiting compound | 莱福斯希医药公司 | 2019-07-16 | — | — | CN | disclosed |