Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27227668 | 1.00 | CXCR3 (0.55) | CXCR3RECQLSMN1; SMN2KDM4EGAA | |
| SCHEMBL30015425 | 0.92 | CXCR3 (0.51) | CXCR3DRD2SIGMAR1ACHE | |
| SCHEMBL26962953 | 0.92 | CXCR3 (0.51) | CXCR3DRD2SIGMAR1ACHE | |
| 1,2,3,4-Tetrahydroisoquinoline SCHEMBL27227665 | 0.90 | CXCR3 (0.48) | CXCR3RECQLSMN1; SMN2KDM4EGAA | |
| SCHEMBL26963042 | 0.90 | CXCR3 (0.49) | CXCR3SMN1; SMN2DRD2DRD4SIGMAR1 | |
| SCHEMBL30014689 | 0.90 | CXCR3 (0.49) | CXCR3SMN1; SMN2DRD2DRD4SIGMAR1 | |
| SCHEMBL6424174 | 0.83 | CXCR3 (0.62) | CXCR3RECQLSMN1; SMN2DRD2DRD3 | |
| SCHEMBL23553483 | 0.83 | SLC18A3 (0.56) | DRD2SIGMAR1 | |
| SCHEMBL30014700 | 0.81 | SIGMAR1 (0.44) | CXCR3DRD2DRD4SIGMAR1ACHE | |
| SCHEMBL26962907 | 0.81 | SIGMAR1 (0.44) | CXCR3DRD2DRD4SIGMAR1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157069-A | Compounds, compositions and methods for modulating FGF activity | 康复治疗公司 | 2023-12-01 | — | — | CN | disclosed |