Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29435969 | 1.00 | TDP1 (0.67) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL30490230 | 0.85 | TDP1 (0.57) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL8013048 | 0.85 | TDP1 (0.57) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL306584 | 0.83 | TDP1 (0.67) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL29417506 | 0.83 | TDP1 (0.67) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL308086 | 0.83 | TDP1 (0.50) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL29705108 | 0.83 | TDP1 (0.50) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL18663666 | 0.82 | TDP1 (0.53) | TDP1TSHRMAPK1ATMVCAM1 | |
| SCHEMBL278488 | 0.80 | TDP1 (1.00) | TDP1TSHRMAPK1VCAM1ALDH1A1 | |
| SCHEMBL7878524 | 0.80 | TSHR (0.52) | TDP1TSHRMAPK1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114230471-B | Preparation method of 3, 4-dichloro-2-fluoroaniline | 河北科技大学 | 2024-01-26 | — | — | CN | claimed |
| CN-110642720-B | Preparation method of 2, 4-difluoro-3, 5-dichloronitrobenzene | 浙江吉泰新材料股份有限公司 | 2022-09-27 | — | — | CN | claimed |
| CN-114230471-A | Preparation method of 3, 4-dichloro-2-fluoroaniline | 河北科技大学 | 2022-03-25 | — | — | CN | claimed |
| CN-107325001-B | Preparation method of 2,3, 4-trifluoronitrobenzene | 浙江解氏新材料股份有限公司 | 2020-03-06 | — | — | CN | claimed |
| CN-110642720-A | Preparation method of 2, 4-difluoro-3, 5-dichloronitrobenzene | 浙江林江化工股份有限公司 | 2020-01-03 | — | — | CN | claimed |
| CN-102911080-B | Method for preparing 2,6-dichloro-alpha-(4-chlorphenyl)-4-nitro phenylacetonitrile | UNIV QUZHOU | 2015-01-21 | — | — | CN | claimed |
| CN-117486670-B | Synthesis method of 3,4, 5-trifluoro-bromobenzene | 山东国邦药业有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117486670-A | Synthesis method of 3,4, 5-trifluoro-bromobenzene | 山东国邦药业有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-114230471-B | Preparation method of 3, 4-dichloro-2-fluoroaniline | 河北科技大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114230471-B | Preparation method of 3, 4-dichloro-2-fluoroaniline | 河北科技大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-110642720-B | Preparation method of 2, 4-difluoro-3, 5-dichloronitrobenzene | 浙江吉泰新材料股份有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-110642720-B | Preparation method of 2, 4-difluoro-3, 5-dichloronitrobenzene | 浙江吉泰新材料股份有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114230471-A | Preparation method of 3, 4-dichloro-2-fluoroaniline | 河北科技大学 | 2022-03-25 | — | — | CN | disclosed |
| US-6458990-B1 | BIS(DIHYDROCARBYLAMINO)DIFLUOROMETHANE OR CYCLIC DERIVATIVES THEREOF; FORMING BY REACTING ALKALI METAL HALIDE WITH THE CORRESPONDING AMIDINIUM SALT; FLUORINATION OF ALCOHOLS, THIOPHENOLS, ALDEHYDES, AND KETONES | MITSUI CHEMICALS, INC. (JP) | 2002-10-01 | — | — | US | disclosed |
| US-20020042521-A1 | Nitrogen-based halogenating agents and process for preparing halogen-containing compounds | SONODA HIROSHI (JP) | 2002-04-11 | — | — | US | disclosed |
| EP-1165504-A2 | INHIBITORS OF LFA-1 BINDING TO ICAMs AND USES THEREOF | ICOS CORPORATION (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6329529-B1 | FOR FLUORINATING OF ORGANIC COMPOUNDS, EFFICIENCY, POLLUTION CONTROL | MITSUI CHEMICALS, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1097914-A2 | Process for the treatment of reaction mixtures, obtained by halogen exchange reactions | Clariant GmbH (DE) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000059878-A2 | INHIBITORS OF LFA-1 BINDING TO ICAMs AND USES THEREOF | ICOS CORPORATION (US) | 2000-10-12 | — | — | WO | disclosed |
| EP-0895991-A2 | Halogenating agent | Mitsui Chemicals, Inc. (JP) | 1999-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020042521-A1 | Nitrogen-based halogenating agents and process for preparing halogen-containing compounds | AFF1, NAF1, CYP2F1 | TDP1 2233/4885TSHR 984/4885MAPK1 444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.