Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.57 |
| ▸ | MYC | P01106 | 2/20 | 0.55 |
| ▸ | MAX | P61244 | 2/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528040 | 1.00 | EP300 (0.61) | EP300HIF1ACASP6TSHRPDK1 | |
| SCHEMBL2550259 | 0.88 | PDK1 (0.72) | EP300HIF1ACASP6TSHRPDK1 | |
| SCHEMBL527425 | 0.86 | HCAR3 (0.55) | EP300HIF1ACASP6TSHRMYC | |
| SCHEMBL28107004 | 0.86 | MAPK1 (0.58) | EP300HIF1ATSHRPDK1MYC | |
| SCHEMBL1560385 | 0.85 | AR (0.58) | EP300HIF1APDK1MYCMAX | |
| SCHEMBL17775445 | 0.85 | PDK1 (0.54) | EP300HIF1ACASP6TSHRPDK1 | |
| SCHEMBL16392507 | 0.85 | PDK1 (0.54) | EP300HIF1ATSHRPDK1MYC | |
| SCHEMBL16974724 | 0.85 | CASP6 (0.63) | EP300HIF1ACASP6TSHRMYC | |
| SCHEMBL31003858 | 0.85 | CASP6 (0.63) | EP300HIF1ACASP6TSHRMYC | |
| SCHEMBL223878 | 0.83 | TTR (0.64) | CASP6TSHRMYCMAXHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230059-A1 | MDM2 DEGRADER | NEWAVE PHARMACEUTICAL INC. (US) | 2023-11-30 | — | — | WO | disclosed |