SCHEMBL3065993

SCHEMBL3065993

O=C(OCc1cccc(C(F)(F)F)c1)C(Cn1ccnc1)C(O)c1cccnc1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.41
CYP11B1 P15538 3/20 0.41
CYP11B2 P19099 3/20 0.41
FFAR1 O14842 1/20 0.41
KCNA5 P22460 1/20 0.39
PRKCA P17252 1/20 0.39
PRKCD Q05655 1/20 0.39
IDO1 P14902 2/20 0.38
MMP1 P03956 1/20 0.38
MMP12 P39900 1/20 0.38
TBXAS1 P24557 1/20 0.37
HRH4 Q9H3N8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3071472 0.85 FFAR1 (0.41) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL6308384 0.84 FFAR1 (0.40) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL3075533 0.83 FFAR1 (0.46) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL6317294 0.82 CYP19A1 (0.44) CYP19A1CYP11B1CYP11B2FFAR1PRKCA
SCHEMBL3076925 0.82 MEN1 (0.41) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL3072922 0.82 FFAR1 (0.39) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL6309762 0.81 PRKCA (0.46) FFAR1KCNA5PRKCAPRKCDIDO1
SCHEMBL3069083 0.79 KCNA5 (0.44) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL3076912 0.79 FFAR1 (0.43) FFAR1KCNA5PRKCAPRKCDMMP1
SCHEMBL3062239 0.79 FFAR1 (0.47) FFAR1KCNA5PRKCAPRKCDMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100267555-A1 Fungicidal mixtures II BASF SE (DE) 2010-10-21 US claimed
EP-2222169-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2010-09-01 EP claimed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 WO claimed
US-20100267555-A1 Fungicidal mixtures II BASF SE (DE) 2010-10-21 US disclosed
EP-2222169-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2010-09-01 EP disclosed
WO-2009063075-A2 FUNGICIDAL MIXTURES II BASF SE (DE) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267555-A1 Fungicidal mixtures II CBR3, CBR1, NOX3 CYP19A1 428/4885CYP11B1 109/4885CYP11B2 138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.