Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369523 | 0.90 | BRD4 (0.46) | BRD4ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL28510085 | 0.84 | KDM4E (0.48) | BRD4NR1H2NR1H3PTPN1ALDH1A1 | |
| SCHEMBL16057538 | 0.76 | MAPT (0.40) | BRD4ALDH1A1L3MBTL1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL30661789 | 0.74 | TYMP (0.40) | ALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL12505693 | 0.72 | BRD4 (0.46) | BRD4CES1ALDH1A1KDM4EHPGD | |
| SCHEMBL27999695 | 0.71 | LIPG (0.53) | NR1H2NR1H3PTPN1 | |
| SCHEMBL30661774 | 0.68 | NR1H2 (0.49) | NR1H2NR1H3ALDH1A1L3MBTL1HPGD | |
| SCHEMBL23400246 | 0.68 | NPC1 (0.40) | BRD4TLR8ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL1840439 | 0.68 | PPARA (0.45) | KDM4E | |
| SCHEMBL1834010 | 0.68 | PPARA (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157285-A | Pharmaceutical compounds as ubiquitin-specific protease 19 (USP 19) inhibitors | 阿尔麦克探索有限公司 | 2023-12-01 | — | — | CN | disclosed |