Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | STAT5B | P51692 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24682934 | 1.00 | TSPO (0.39) | TSPOAKT1PDK1GRM6DYRK1A | |
| SCHEMBL24682178 | 0.89 | MAPT (0.43) | TSPOPDK1DYRK1AESR1ESR2 | |
| SCHEMBL29800041 | 0.89 | MAPT (0.43) | TSPOPDK1DYRK1AESR1ESR2 | |
| SCHEMBL29799804 | 0.88 | TSPO (0.44) | TSPOPDK1DYRK1AESR1ESR2 | |
| SCHEMBL24682174 | 0.88 | TSPO (0.44) | TSPOPDK1DYRK1AESR1ESR2 | |
| SCHEMBL24683154 | 0.87 | LMNA (0.45) | TSPOPDK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL29800048 | 0.87 | LMNA (0.45) | TSPOPDK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL24682961 | 0.86 | POLB (0.39) | TSPOPDK1DYRK1AESR1ESR2 | |
| SCHEMBL30664676 | 0.86 | POLB (0.39) | TSPOPDK1DYRK1AESR1ESR2 | |
| SCHEMBL24682194 | 0.84 | TSPO (0.42) | TSPOPDK1DYRK1AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174629-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | OTCPHARM JSC (RU) | 2024-05-30 | — | — | US | disclosed |
| EP-4293017-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Otcpharm JSC (RU) | 2023-12-20 | — | — | EP | disclosed |
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174629-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | ACE2, ACE, EIF2AK2 | TSPO 4234/4885AKT1 4140/4885PDK1 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.