Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 8/20 | 0.52 |
| ▸ | DRD2 | P14416 | 10/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30665179 | 0.97 | BPTF (0.52) | BPTFDRD2KAT2BBRD9BRD4 | |
| SCHEMBL30665178 | 0.91 | BPTF (0.51) | BPTFDRD2KAT2BBRD9BRD4 | |
| SCHEMBL26911046 | 0.89 | BPTF (0.57) | BPTFDRD2KAT2BBRD9BRD4 | |
| SCHEMBL30665181 | 0.88 | BPTF (0.51) | BPTFDRD2KAT2BBRD9BRD4 | |
| SCHEMBL26911780 | 0.86 | BPTF (0.57) | BPTFKAT2BBRD9BRD4 | |
| SCHEMBL26911297 | 0.80 | BPTF (0.55) | BPTFKAT2BBRD9BRD4 | |
| SCHEMBL26911344 | 0.77 | BPTF (0.55) | BPTFKAT2BBRD9BRD4 | |
| SCHEMBL31735467 | 0.74 | BPTF (0.57) | BPTFKAT2BBRD9BRD4 | |
| SCHEMBL15830562 | 0.71 | DRD2 (0.63) | DRD2 | |
| SCHEMBL31735413 | 0.71 | BPTF (0.95) | BPTFKAT2BBRD9BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391745-A1 | SMALL MOLECULE DEGRADERS OF THE BROMODOMAIN AND PHD FINGER TRANSCRIPTION FACTOR | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2023-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391745-A1 | SMALL MOLECULE DEGRADERS OF THE BROMODOMAIN AND PHD FINGER TRANSCRIPTION FACTOR | BPTF, BRPF3, CECR2 | BPTF 1/4885DRD2 2846/4885KAT2B 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.