SCHEMBL31735467

SCHEMBL31735467

Cn1ncc(Nc2ccc3c(c2)CCN3C(=O)OC(C)(C)C)c(Cl)c1=O

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ BPTF Q12830 13/20 0.57
▸ KAT2B Q92831 7/20 0.47
▸ BRD9 Q9H8M2 6/20 0.47
▸ BRD4 O60885 5/20 0.47
▸ KAT2A Q92830 1/20 0.43
▸ CECR2 Q9BXF3 1/20 0.43
▸ BRD7 Q9NPI1 1/20 0.43
▸ JAK2 O60674 1/20 0.39
▸ JAK3 P52333 1/20 0.39
▸ PTK2 Q05397 1/20 0.39
▸ PLK1 P53350 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28359226 0.76 GPR119 (0.40) PLK1
SCHEMBL31735584 0.76 BPTF (0.68) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL30665179 0.74 BPTF (0.52) BPTFKAT2BBRD9BRD4
SCHEMBL30665182 0.74 BPTF (0.52) BPTFKAT2BBRD9BRD4
SCHEMBL31735373 0.74 ESR2 (0.53) BPTFBRD9BRD4JAK2JAK3
SCHEMBL12464373 0.73 ALDH1A1 (0.53) —
SCHEMBL31735413 0.73 BPTF (0.95) BPTFKAT2BBRD9BRD4KAT2A
SCHEMBL31735624 0.73 WEE1 (0.46) BPTFKAT2BBRD9BRD4
SCHEMBL27975558 0.73 NOTUM (0.65) —
SCHEMBL17794739 0.71 BRD4 (0.49) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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