SCHEMBL30666830

SCHEMBL30666830

Cc1cccc(C2=Cc3ccccc3C2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.53
CYP11B2 P19099 4/20 0.53
PTGS2 P35354 2/20 0.45
IP6K1 Q92551 1/20 0.44
IP6K3 Q96PC2 1/20 0.44
CYP19A1 P11511 2/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NISCH Q9Y2I1 2/20 0.37
ACHE P22303 1/20 0.37
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
FYN P06241 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
DYRK1B Q9Y463 1/20 0.36
ADORA1 P30542 1/20 0.35
DRD2 P14416 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280771 0.86 CYP11B1 (0.51) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL29897853 0.86 CYP11B1 (0.51) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL6285178 0.82 CYP11B1 (0.56) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL6287169 0.82 CYP11B1 (0.54) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL30487694 0.82 CYP11B1 (0.54) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL30667024 0.79 CYP11B1 (0.53) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL319265 0.79 CYP11B2 (0.65) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL31608568 0.79 CYP11B2 (0.65) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL30666878 0.79 CYP11B2 (0.53) CYP11B1CYP11B2PTGS2IP6K1IP6K3
SCHEMBL31666281 0.77 CYP11B2 (0.62) CYP11B1CYP11B2PTGS2IP6K1IP6K3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119824435-A Method for preparing deuterated compound through Berch-type reduction reaction under condition of no transition metal and deuterated compound obtained by method 中国科学院理化技术研究所 2025-04-15 CN disclosed
CN-116940552-A Spirocyclic hexane derivatives, pharmaceutical compositions containing them and their use as anti-apoptotic inhibitors 法国施维雅药厂 2023-10-24 CN disclosed