SCHEMBL6285178

SCHEMBL6285178

C1=C(c2cccc(-c3ccccc3)c2)Cc2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.56
CYP11B2 P19099 4/20 0.56
IP6K1 Q92551 1/20 0.49
IP6K3 Q96PC2 1/20 0.49
PTGS2 P35354 2/20 0.44
MAOA P21397 2/20 0.42
MAOB P27338 1/20 0.42
CYP19A1 P11511 2/20 0.39
KMO O15229 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
NISCH Q9Y2I1 1/20 0.35
GPR84 Q9NQS5 1/20 0.33
TDP2 O95551 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6285180 0.86 CYP11B2 (0.61) CYP11B1CYP11B2IP6K1IP6K3PTGS2
SCHEMBL8058170 0.86 CYP11B2 (0.61) CYP11B1CYP11B2IP6K1IP6K3PTGS2
SCHEMBL31608568 0.86 CYP11B2 (0.65) CYP11B1CYP11B2IP6K1IP6K3PTGS2
SCHEMBL319265 0.86 CYP11B2 (0.65) CYP11B1CYP11B2IP6K1IP6K3PTGS2
SCHEMBL31666281 0.84 CYP11B2 (0.62) CYP11B1CYP11B2IP6K1IP6K3PTGS2
SCHEMBL30667024 0.82 CYP11B1 (0.53) CYP11B1CYP11B2IP6K1IP6K3PTGS2
SCHEMBL30666830 0.82 CYP11B1 (0.53) CYP11B1CYP11B2IP6K1IP6K3PTGS2
SCHEMBL7091160 0.80 KMO (0.53) CYP11B1CYP11B2IP6K1IP6K3MAOA
SCHEMBL30666878 0.78 CYP11B2 (0.53) CYP11B1CYP11B2IP6K1IP6K3PTGS2
SCHEMBL29115236 0.78 CYP11B1 (0.49) CYP11B1CYP11B2IP6K1IP6K3PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1120182-C Thermoplastic elastic stereoblock olefin polymer, preparation method and metallocene catalyst UNIV LELAND STANFORD JUNIOR (US) 2003-09-03 CN claimed
US-6518378-B2 Using an unbridged cyclopentadienyl metallocene catalyst capable of interconverting between states with different copolymerization characteristics THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-02-11 US claimed
US-6479685-B2 POLYMERIZING ETHYLENE AND ANOTHER ALPHA-OLEFIN IN THE PRESENCE OF AN UNBRIDGED, ROTATING, NON-RIGID FLUXIONAL METALLOCENE CATALYST COMPONENT AND A CO-CATALYST THE BOARD OF TRUSTEES OF THE LELAND STANDARD JUNIOR UNIVERSITY 2002-11-12 US claimed
US-20010049425-A1 High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis BP CORPORATION NORTH AMERICA INC. 2001-12-06 US claimed
US-20010034426-A1 High-melting polyolefin copolymer elastomers, catalysts and methods of synthesis BP CORPORATION NORTH AMERICA INC. 2001-10-25 US claimed
US-6169151-B1 MADE BY POLYMERIZING ETHYLENE AND ALPHA-OLEFIN(S) USING AN UNBRIDGED, ROTATING, NON-RIGID FLUXIONAL METALLOCENE CATALYST AND COCATALYST; CRYSTALLIZABLE ELASTOMERIC COPOLYMER PRODUCT HAS HIGHER MELTING POINT, NARROW COMPOSITION DISTRIBUTION THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2001-01-02 US claimed
WO-1999035171-A1 HIGH-MELTING POLYOLEFIN COPOLYMER ELASTOMERS, CATALYSTS AND METHODS OF SYNTHESIS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY (US) 1999-07-15 WO claimed
EP-0802935-A4 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS UNIV LELAND STANFORD JUNIOR (US) 1998-09-30 EP claimed
CN-1172488-A Thermoplastic elastomeric stereoblock olefin polymers methods and metallocene catalysts TRUSTEES FO THE LELAND STANFOR (US) 1998-02-04 CN claimed
EP-0802935-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1997-10-29 EP claimed
US-5594080-A POLYMERIZATION CATALYSIS OF METALLOCENES WITH CYCLOPENTADIENE AND METALS LELAND STANFORD, JR. UNIVERSITY (US) 1997-01-14 US claimed
WO-1995025757-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1995-09-28 WO claimed
US-6960550-B2 Catalyst systems for high melting thermoplastic elastomeric α-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2005-11-01 US disclosed
US-20030195308-A1 Catalyst systems for high melting thermoplastic elastomeric alpha-olefin polymers and plastomers THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-10-16 US disclosed
CN-1120182-C Thermoplastic elastic stereoblock olefin polymer, preparation method and metallocene catalyst UNIV LELAND STANFORD JUNIOR (US) 2003-09-03 CN disclosed
US-6566544-B1 Indene ring-containing metallocene-complex catalysts THE BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY 2003-05-20 US disclosed
CN-1172488-A Thermoplastic elastomeric stereoblock olefin polymers methods and metallocene catalysts TRUSTEES FO THE LELAND STANFOR (US) 1998-02-04 CN disclosed
EP-0802935-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1997-10-29 EP disclosed
US-5594080-A POLYMERIZATION CATALYSIS OF METALLOCENES WITH CYCLOPENTADIENE AND METALS LELAND STANFORD, JR. UNIVERSITY (US) 1997-01-14 US disclosed
WO-1995025757-A1 THERMOPLASTIC ELASTOMERIC STEREOBLOCK OLEFIN POLYMERS METHODS AND METALLOCENE CATALYSTS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1995-09-28 WO disclosed