Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7484668 | 0.99 | ALDH1A1 (0.44) | ALDH1A1MAPK1EPHX1EPHX2ABCB1 | |
| SCHEMBL3069255 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPK1EPHX1EPHX2ABCB1 | |
| Hydrochloric Acid SCHEMBL8791052 | 0.79 | ABCB1 (0.44) | ALDH1A1ABCB1L3MBTL1HPGDCYP3A4 | |
| SCHEMBL7525072 | 0.79 | ABCB1 (0.38) | ALDH1A1MAPK1ABCB1L3MBTL1CYP3A4 | |
| SCHEMBL8609012 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPK1EPHX1EPHX2ABCB1 | |
| SCHEMBL5214576 | 0.74 | ABCB1 (0.44) | ALDH1A1ABCB1HPGDCYP3A4 | |
| SCHEMBL5144569 | 0.72 | MAPT (0.44) | ALDH1A1ABCB1HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL9329853 | 0.71 | ABCB1 (0.53) | ALDH1A1ABCB1RAB9ASMN1; SMN2CYP3A4 | |
| SCHEMBL5144884 | 0.71 | ABCB1 (0.44) | ALDH1A1ABCB1L3MBTL1HPGDCYP3A4 | |
| SCHEMBL10555746 | 0.71 | SLC18A3 (0.56) | ALDH1A1ABCB1L3MBTL1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267711-A1 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF | CYTRX CORPORATION (US) | 2010-10-21 | — | — | US | disclosed |
| US-7745465-B2 | Method of enhancing cellular production of molecular chaperone, hydroxylamine derivatives useful for enhancing the chaperone production and the preparation thereof | CYTRX CORPORATION (US) | 2010-06-29 | — | — | US | disclosed |
| US-7148239-B2 | Method of enhancing cellular production of molecular chaperon, hydroxylamine derivatives useful for enhancing the chaperon production and the preparation thereof | CYTRX CORPORATION (US) | 2006-12-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267711-A1 | METHOD OF ENHANCING CELLULAR PRODUCTION OF MOLECULAR CHAPERONE, HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE CHAPERONE PRODUCTION AND THE PREPARATION THEREOF | HSPE1, HSF1, HSP90AB2P | ALDH1A1 533/4885MAPK1 3049/4885EPHX1 2282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.