Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069255 | 0.95 | ALDH1A1 (0.49) | ALDH1A1MAPK1SMN1; SMN2HTTPKM | |
| SCHEMBL3066709 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPK1SMN1; SMN2ABCB1EPHX1 | |
| Hydrochloric Acid SCHEMBL7484668 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPK1ABCB1EPHX1EPHX2 | |
| SCHEMBL3060825 | 0.77 | MEN1 (0.64) | ALDH1A1SMN1; SMN2PKMABCB1RAB9A | |
| SCHEMBL11480838 | 0.77 | MEN1 (0.64) | ALDH1A1SMN1; SMN2PKMABCB1RAB9A | |
| SCHEMBL7526130 | 0.76 | ABCB1 (0.49) | ALDH1A1PKMABCB1MEN1KMT2A | |
| SCHEMBL7530991 | 0.75 | ABCB1 (0.48) | ALDH1A1PKMABCB1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29215641 | 0.75 | KMT2A (0.61) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL14538079 | 0.75 | KMT2A (0.60) | SMN1; SMN2HTTMEN1KMT2AKDM4E | |
| SCHEMBL8608808 | 0.74 | KDM4E (0.45) | ALDH1A1ABCB1EPHX1EPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832079-A1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO ES FEJLESZTÖ RT. (HU) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997000251-A1 | ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS | BIOREX KUTATO ES FEJLESZTO RT. (HU) | 1997-01-03 | — | — | WO | disclosed |